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Systems Biology

Press Releases

Georgia Tech Creates Integrative BioSystems Institute

February 7, 2008 — The Georgia Institute of Technology has created the Integrative BioSystems Institute (IBSI) to explore new technologies and methods to collect and analyze the enormous amounts of data in biological systems to form a more complete picture of how life works and how the environment affects living things. IBSI represents a major investment of at least $100 million by Georgia Tech over the next several years.

Georgia Tech Creates New Ph.D. in Computational Science and Engineering

February 13, 2008 — The Colleges of Computing, Engineering, and Sciences at Georgia Tech today announced the creation of a new doctoral degree in Computational Science and Engineering (CSE), a cooperative, truly interdisciplinary effort between the three academic units. Georgia Tech is an established leader in the fields of engineering and sciences, and is quickly becoming recognized for defining the direction of the computing discipline. "Computation, through modeling, simulation, analysis and its other forms, is essential in creating new applications with great impact on the sustainable growth of cities, the design of power-efficient buildings, the creation of new biomedical devices, the eradication of life-threatening diseases and other issues of great social importance," said Richard Fujimoto, the Chair of CSE.

Georgia Tech Accelerates Drug Discovery with Supercomputer

February 8, 2006 — IBM and the Georgia Institute of Technology have announced that one of the world's most powerful supercomputing clusters will anchor Georgia Tech's new Center for the Study of Systems Biology. The Center will use IBM technologies to advance research into new drugs for the treatment of some of today's most life-threatening diseases, including cancer. The Center's research will be headed by one of the world's leading systems biologists, Dr. Jeffrey Skolnick, the Georgia Research Alliance Eminent Scholar in Computational Systems Biology.

Scientists Model 900 Cell Receptors, Drug Targets

February 17, 2006 — In an important step toward accelerating drug discovery, researchers have created computer models of more than 900 cell receptors from a class of proteins known to be important drug targets. The models, which are now freely available to noncommercial users, promise to help scientists narrow their research inquiries, potentially speeding up the discovery of new drug compounds.

Georgia Tech Creates Self-Training Gene Prediction Program

June 16, 2006 — Researchers at the Georgia Institute of Technology have developed the first ever computer program capable of training itself to predict genes in genomic DNA sequences of eukaryotic organisms such as animals, plants and fungi. The software program, GeneMark.hmm-ES, may help researchers save a year or more in a genome sequencing and interpretation project. The program is a new addition to the family of GeneMark gene prediction programs developed at Georgia Tech and is freely available to academic researchers.

Scientists Uncover Rules for Gene Amplification

June 29, 2006 — Gene amplification plays an important role in causing cancers via activation of oncogenes. If scientists can determine the rules as to which segments of genetic material become amplified and how, oncologists and drug researchers may be able to interrupt that process and prevent the formation and growth of some tumors. Using yeast as a model organism, researchers at the Georgia Institute of Technology have discovered that the location of a hairpin-capped break relative to the end of the chromosome will determine the fate of the amplification event.

Integrative BioSystems Institute

The Integrative BioSystems Institute (IBSI) at Georgia Tech is a forum for multi-scale, multi-disciplinary systems approaches toward solutions of grand-challenge problems in biology. IBSI's main focus is the development and application of enabling technologies that are needed to solve some of the grand-challenge questions of biology and medicine of the 21st century. Our initial target applications are developmental processes leading to cancer and the interactions between humans and microbial systems in the environment. Accompanying and supporting these threads are initiatives in high-performance computing, computational modeling, and the creation of macro-, micro- and nano-devices for biosystems research.

Georgia Tech Center for Bioinformatics and Computational Genomics

The Center for Bioinformatics and Computational Genomics at Georgia Tech has been formed to facilitate collaborative research in the interdisciplinary area of bioinformatics and computational genomics and to create an intellectual environment for interdisciplinary education and training of the MS and PhD students in Bioinformatics. The Center is comprised of the Georgia Tech faculty with research interests in bioinformatics and computational genomics.

Mark Borodovsky, Director
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School of Biology and Biomedical Engineering
Phone: (404) 894-8432

People

Eberhard Voit

Director, Ingrative BioSystems Institute,
Professor, Biomedical Engineering
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Jeffrey Skolnick

Director, Center for the Study of Systems Biology
Associate Director, Integrative BioSystems Institute
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Richard Fujimoto

Professor and Chair of the Computational Science and Engineering Division, College of Computing
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Mark Borodovsky

Director, Center for Bioinformatics and Computational Genomics
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